Impaired CENP-E Function Renders Large Chromosomes More Vulnerable to Congression Failure

It has recently emerged that human chromosomes vary between one another in terms of features that impact their behaviour during impaired chromosome segregation, leading to non-random aneuploidy in the daughter cell population. During the process of chromosome congression to the metaphase plate, chro...

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Bibliographic Details
Main Authors: Laura Tovini, Sarah E. McClelland
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/9/2/44