Acss2/HIF-2 signaling facilitates colon cancer growth and metastasis

Acss2/HIF-2 signaling facilitates colon cancer growth and metastasis

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The microenvironment of solid tumors is characterized by oxygen and glucose deprivation. Acss2/HIF-2 signaling coordinates essential genetic regulators including acetate-dependent acetyl CoA synthetase 2 (Acss2), Creb binding protein (Cbp), Sirtuin 1 (Sirt1), and Hypoxia Inducible Factor 2α (HIF-2α)...

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Bibliographic Details
Main Authors: Joseph A. Garcia, Rui Chen, Min Xu, Sarah A. Comerford, Robert E. Hammer, Shelby D. Melton, Linda A. Feagins
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980813/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9980813/?tool=EBI

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