Evaluation of Depigmenting Activity by 8-Hydroxydaidzein in Mouse B16 Melanoma Cells and Human Volunteers

In our previous study, 8-hydroxydaidzein (8-OHDe) was demonstrated to be a potent and unique suicide substrate of mushroom tyrosinase. In this study, the compound was evaluated for in vitro cellular tyrosinase and melanogenesis inhibitory activities in mouse B16 melanoma cells and for in vivo skin-w...

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Bibliographic Details
Main Authors: Ching-Gong Lin, Mon-Han Wu, Te-Sheng Chang, Sorgan Shou-Ku Tai
Format: Article
Language:English
Published: MDPI AG 2009-09-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/10/10/4257/