Inactivation of the Response Regulator AgrA Has a Pleiotropic Effect on Biofilm Formation, Pathogenesis and Stress Response in Staphylococcus lugdunensis

Inactivation of the Response Regulator AgrA Has a Pleiotropic Effect on Biofilm Formation, Pathogenesis and Stress Response in Staphylococcus lugdunensis

ABSTRACT Staphylococcus lugdunensis is a coagulase-negative Staphylococcus that emerges as an important opportunistic pathogen. However, little is known about the regulation underlying the transition from commensal to virulent state. Based on knowledge of S. aureus virulence, we suspected that the a...

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Bibliographic Details
Main Authors: Marion Aubourg, Marine Pottier, Albertine Léon, Benoit Bernay, Anne Dhalluin, Margherita Cacaci, Riccardo Torelli, Pierre Ledormand, Cecilia Martini, Maurizio Sanguinetti, Michel Auzou, François Gravey, Jean-Christophe Giard
Format: Article
Language:English
Published: American Society for Microbiology 2022-02-01
Series:Microbiology Spectrum
Subjects:
Staphylococcus lugdunensis
AgrA
transcriptional regulation
agr system
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01598-21

Internet

https://journals.asm.org/doi/10.1128/spectrum.01598-21

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