"Deep" sequencing accuracy and reproducibility using Roche/454 technology for inferring co-receptor usage in HIV-1.

Next generation, "deep", sequencing has increasing applications both clinically and in disparate fields of research. This study investigates the accuracy and reproducibility of "deep" sequencing as applied to co-receptor prediction using the V3 loop of Human Immunodeficiency Viru...

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Bibliographic Details
Main Authors: David J H F Knapp, Rachel A McGovern, Art F Y Poon, Xiaoyin Zhong, Dennison Chan, Luke C Swenson, Winnie Dong, P Richard Harrigan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4069016?pdf=render