Ablation and antiarrhythmic drug effects on PITX2+/− deficient atrial fibrillation: A computational modeling study

Ablation and antiarrhythmic drug effects on PITX2+/− deficient atrial fibrillation: A computational modeling study

IntroductionAtrial fibrillation (AF) is a heritable disease, and the paired-like homeodomain transcription factor 2 (PITX2) gene is highly associated with AF. We explored the differences in the circumferential pulmonary vein isolation (CPVI), which is the cornerstone procedure for AF catheter ablati...

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Bibliographic Details
Main Authors: Ze Jin, Inseok Hwang, Byounghyun Lim, Oh-Seok Kwon, Je-Wook Park, Hee-Tae Yu, Tae-Hoon Kim, Boyoung Joung, Moon-Hyoung Lee, Hui-Nam Pak
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
atrial fibrillation
computational modeling
PITX2
dominant frequency
antiarrhythmic drug
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.942998/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2022.942998/full

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