Retrospective evaluation and prediction of clearance and toxicity of high dose methotrexate in childhood acute lymphoblastic leukemia patients

To find the predictors of High Dose Methotrexate toxicities in childhood Acute Lymphoblastic Leukemia Patients. This study included 198 Childhood Acute Lymphoblastic Leukemia patients (303 infusions) who were treated with High Dose Methotrexate. Methotrexate levels at different time point were measu...

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Bibliographic Details
Main Authors: Yuxia Shan, Hui Gao, Zhong Li, Jinghua Li, Yang Liu, Lujuan Li, Qi Zhang
Format: Article
Language:English
Published: Universidade de São Paulo 2021-04-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100616&tlng=en