The Mitochondrial m-AAA Protease Prevents Demyelination and Hair Greying.

The m-AAA protease preserves proteostasis of the inner mitochondrial membrane. It ensures a functional respiratory chain, by controlling the turnover of respiratory complex subunits and allowing mitochondrial translation, but other functions in mitochondria are conceivable. Mutations in genes encodi...

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Bibliographic Details
Main Authors: Shuaiyu Wang, Julie Jacquemyn, Sara Murru, Paola Martinelli, Esther Barth, Thomas Langer, Carien M Niessen, Elena I Rugarli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-12-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5135034?pdf=render