PTHrP promotes subchondral bone formation in TMJ-OA

Abstract PTH-related peptide (PTHrP) improves the bone marrow micro-environment to activate the bone-remodelling, but the coordinated regulation of PTHrP and transforming growth factor-β (TGFβ) signalling in TMJ-OA remains incompletely understood. We used disordered occlusion to establish model anim...

Full description

Bibliographic Details
Main Authors: Jun Zhang, Caixia Pi, Chen Cui, Yang Zhou, Bo Liu, Juan Liu, Xin Xu, Xuedong Zhou, Liwei Zheng
Format: Article
Language:English
Published: Nature Publishing Group 2022-07-01
Series:International Journal of Oral Science
Online Access:https://doi.org/10.1038/s41368-022-00189-x