Parsimonious Clone Tree Integration in cancer

Abstract Background Every tumor is composed of heterogeneous clones, each corresponding to a distinct subpopulation of cells that accumulated different types of somatic mutations, ranging from single-nucleotide variants (SNVs) to copy-number aberrations (CNAs). As the analysis of this intra-tumor he...

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Bibliographic Details
Main Authors: Palash Sashittal, Simone Zaccaria, Mohammed El-Kebir
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Algorithms for Molecular Biology
Subjects:
Online Access:https://doi.org/10.1186/s13015-022-00209-9