Parsimonious Clone Tree Integration in cancer
Abstract Background Every tumor is composed of heterogeneous clones, each corresponding to a distinct subpopulation of cells that accumulated different types of somatic mutations, ranging from single-nucleotide variants (SNVs) to copy-number aberrations (CNAs). As the analysis of this intra-tumor he...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-03-01
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Series: | Algorithms for Molecular Biology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13015-022-00209-9 |