Characteristics of the GlnH and GlnX Signal Transduction Proteins Controlling PknG-Mediated Phosphorylation of OdhI and 2-Oxoglutarate Dehydrogenase Activity in Corynebacterium glutamicum

Characteristics of the GlnH and GlnX Signal Transduction Proteins Controlling PknG-Mediated Phosphorylation of OdhI and 2-Oxoglutarate Dehydrogenase Activity in Corynebacterium glutamicum

ABSTRACT In Corynebacterium glutamicum the protein kinase PknG phosphorylates OdhI and thereby abolishes the inhibition of 2-oxoglutarate dehydrogenase activity by unphosphorylated OdhI. Our previous studies suggested that PknG activity is controlled by the periplasmic binding protein GlnH and the t...

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Bibliographic Details
Main Authors: Lea Sundermeyer, Graziella Bosco, Srushti Gujar, Melanie Brocker, Meike Baumgart, Dieter Willbold, Oliver H. Weiergräber, Marco Bellinzoni, Michael Bott
Format: Article
Language:English
Published: American Society for Microbiology 2022-12-01
Series:Microbiology Spectrum
Subjects:
bacterial signaling
Corynebacterium glutamicum
2-oxoglutarate dehydrogenase
protein phosphorylation
periplasmic binding protein
Actinobacteria
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02677-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.02677-22

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