SNPs array karyotyping reveals a novel recurrent 20p13 amplification in primary myelofibrosis.

SNPs array karyotyping reveals a novel recurrent 20p13 amplification in primary myelofibrosis.

The molecular pathogenesis of primary mielofibrosis (PMF) is still largely unknown. Recently, single-nucleotide polymorphism arrays (SNP-A) allowed for genome-wide profiling of copy-number alterations and acquired uniparental disomy (aUPD) at high-resolution. In this study we analyzed 20 PMF patient...

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Bibliographic Details
Main Authors: Giuseppe Visani, Maria Rosaria Sapienza, Alessandro Isidori, Claudio Tripodo, Maria Antonella Laginestra, Simona Righi, Carlo A Sagramoso Sacchetti, Anna Gazzola, Claudia Mannu, Maura Rossi, Michele De Nictolis, Massimo Valentini, Meris Donati, Roberto Emiliani, Francesco Alesiani, Stefania Paolini, Carlo Finelli, Stefano A Pileri, Pier Paolo Piccaluga
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3215741?pdf=render

Internet

http://europepmc.org/articles/PMC3215741?pdf=render

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