Targeting extracellular CIRP with an X-aptamer shows therapeutic potential in acute pancreatitis

Summary: Severe acute pancreatitis (AP) is associated with a high mortality rate. Cold-inducible RNA binding protein (CIRP) can be released from cells in inflammatory conditions and extracellular CIRP acts as a damage-associated molecular pattern. This study aims to explore the role of CIRP in the p...

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Bibliographic Details
Main Authors: Wuming Liu, Jianbin Bi, Yifan Ren, Huan Chen, Jia Zhang, Tao Wang, Mengzhou Wang, Lin Zhang, Junzhou Zhao, Zheng Wu, Yi Lv, Bing Liu, Rongqian Wu
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223011203