Triiodothyronine Acts as a Smart Influencer on Hsp90 via a Triiodothyronine Binding Site

Triiodothyronine Acts as a Smart Influencer on Hsp90 via a Triiodothyronine Binding Site

Microarray-based experiments revealed that thyroid hormone triiodothyronine (T3) enhanced the binding of Cy5-labeled ATP on heat shock protein 90 (Hsp90). By molecular docking experiments with T3 on Hsp90, we identified a T3 binding site (TBS) near the ATP binding site on Hsp90. A synthetic peptide...

Full description

Bibliographic Details
Main Authors: Lu Fan, Athanasia Warnecke, Julia Weder, Matthias Preller, Carsten Zeilinger
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
triiodothyronine
Hsp90
protein microarray
thermophoresis
molecular docking
Online Access:https://www.mdpi.com/1422-0067/23/13/7150

Internet

https://www.mdpi.com/1422-0067/23/13/7150

Similar Items