Biomarker discovery in attention deficit hyperactivity disorder: RNA sequencing of whole blood in discordant twin and case-controlled cohorts

Biomarker discovery in attention deficit hyperactivity disorder: RNA sequencing of whole blood in discordant twin and case-controlled cohorts

Abstract Background A variety of DNA-based methods have been applied to identify genetic markers of attention deficit hyperactivity disorder (ADHD), but the connection to RNA-based gene expression has not been fully exploited. Methods Using well defined cohorts of discordant, monozygotic twins from...

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Bibliographic Details
Main Authors: Timothy A. McCaffrey, Georges St. Laurent, Dmitry Shtokalo, Denis Antonets, Yuri Vyatkin, Daniel Jones, Eleanor Battison, Joel T. Nigg
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Medical Genomics
Subjects:
Attention-deficit/hyperactivity disorder (ADHD)
RNA sequencing
Transcriptome
GIT1
Galactose
Twins
Online Access:http://link.springer.com/article/10.1186/s12920-020-00808-8

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http://link.springer.com/article/10.1186/s12920-020-00808-8

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