Transient microbiota exposures activate dormant Escherichia coli infection in the bladder and drive severe outcomes of recurrent disease.

Pathogens often inhabit the body asymptomatically, emerging to cause disease in response to unknown triggers. In the bladder, latent intracellular Escherichia coli reservoirs are regarded as likely origins of recurrent urinary tract infection (rUTI), a problem affecting millions of women worldwide....

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Bibliographic Details
Main Authors: Nicole M Gilbert, Valerie P O'Brien, Amanda L Lewis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5373645?pdf=render