Consistent Changes in Cortico-Subthalamic Directed Connectivity Are Associated With the Induction of Parkinsonism in a Chronically Recorded Non-human Primate Model

Consistent Changes in Cortico-Subthalamic Directed Connectivity Are Associated With the Induction of Parkinsonism in a Chronically Recorded Non-human Primate Model

Parkinson’s disease is a neurological disease with cardinal motor signs including bradykinesia and tremor. Although beta-band hypersynchrony in the cortico-basal ganglia network is thought to contribute to disease manifestation, the resulting effects on network connectivity are unclear. We examined...

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Bibliographic Details
Main Authors: Joyce Chelangat Bore, Carmen Toth, Brett A. Campbell, Hanbin Cho, Francesco Pucci, Olivia Hogue, Andre G. Machado, Kenneth B. Baker
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Neuroscience
Subjects:
Parkinson’s disease
connectivity
subthalamic nucleus
electrophysiology
Granger causality
coherence
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.831055/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2022.831055/full

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