Exploiting inter-tissue stress signaling mechanisms to preserve organismal proteostasis during aging

Aging results in a decline of cellular proteostasis capacity which culminates in the accumulation of phototoxic material, causing the onset of age-related maladies and ultimately cell death. Mechanisms that regulate proteostasis such as cellular stress response pathways sense disturbances in the pro...

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Bibliographic Details
Main Author: Patricija van Oosten-Hawle
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1228490/full