Exploiting inter-tissue stress signaling mechanisms to preserve organismal proteostasis during aging
Aging results in a decline of cellular proteostasis capacity which culminates in the accumulation of phototoxic material, causing the onset of age-related maladies and ultimately cell death. Mechanisms that regulate proteostasis such as cellular stress response pathways sense disturbances in the pro...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2023-07-01
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Series: | Frontiers in Physiology |
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Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2023.1228490/full |