Thiazole–Chalcone Hybrids as Prospective Antitubercular and Antiproliferative Agents: Design, Synthesis, Biological, Molecular Docking Studies and In Silico ADME Evaluation

Compounds bearing thiazole and chalcone pharmacophores have been reported to possess excellent antitubercular and anticancer activities. In view of this, we designed, synthesized and characterized a novel series of thiazole–chalcone hybrids (<b>1</b>–<b>20</b>) and further ev...

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Bibliographic Details
Main Authors: Ashok Babu Kasetti, Indrajeet Singhvi, Ravindra Nagasuri, Richie R. Bhandare, Afzal B. Shaik
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/26/10/2847