Cardiotonic Pills Plus Recombinant Human Prourokinase Ameliorates Atherosclerotic Lesions in LDLR–/– Mice

Cardiotonic Pills Plus Recombinant Human Prourokinase Ameliorates Atherosclerotic Lesions in LDLR–/– Mice

AimThis study was to explore the protective effects of cardiotonic pills (CP) or/and recombinant human prourokinase (proUK)on the atherosclerosis and the potential underlying mechanism.Methods and ResultsAtherosclerosis was induced in LDLR–/– mice by high fat diet contained 20% lard and 0.5% cholest...

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Bibliographic Details
Main Authors: Jing-Na Deng, Quan Li, Kai Sun, Chun-Shui Pan, Huan Li, Jing-Yu Fan, Gao Li, Bai-He Hu, Xin Chang, Jing-Yan Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Physiology
Subjects:
atherosclerosis
inflammation
ATP-binding cassette gene 8
adipose triglyceride lipase
scavenger receptor A
CD36
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01128/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.01128/full

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