Relationship between vacA Types and Development of Gastroduodenal Diseases

The Helicobacter pylori vacuolating cytotoxin (VacA) is a secreted pore-forming toxin and a major virulence factor in the pathogenesis of H. pylori infection. While VacA is present in almost all strains, only some forms are toxigenic and pathogenic. While vacA and its genotypes are considered as mar...

Full description

Bibliographic Details
Main Authors: Tran Thi Huyen Trang, Tran Thanh Binh, Yoshio Yamaoka
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/8/6/182