Integrated Genome-Wide Analysis of DNA Methylation and Gene Expression in the Hippocampi of 5xFAD Alzheimer’s Disease Mouse Model

Integrated Genome-Wide Analysis of DNA Methylation and Gene Expression in the Hippocampi of 5xFAD Alzheimer’s Disease Mouse Model

Background: DNA methylation forms 5-methylcytosine and its regulation in the hippocampus is critical for learning and memory. Indeed, dysregulation of DNA methylation is associated with neurological diseases. Alzheimer’s disease (AD) is the predominant of dementia and a neurodegenerative disorder. M...

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Bibliographic Details
Main Authors: Sueun Lee, Hae-June Lee, Jin Mi Chun, Bokyung Jung, Jaebum Kim, Changjong Moon, Chul Kim, Joong-Sun Kim
Format: Article
Language:English
Published: IMR Press 2024-07-01
Series:Journal of Integrative Neuroscience
Subjects:
5xfad
dna methylation
gene expression
alzheimer
epigenetics
Online Access:https://www.imrpress.com/journal/JIN/23/7/10.31083/j.jin2307138

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https://www.imrpress.com/journal/JIN/23/7/10.31083/j.jin2307138

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