Tumor Microenvironment-Associated Extracellular Matrix Components Regulate NK Cell Function

Tumor Microenvironment-Associated Extracellular Matrix Components Regulate NK Cell Function

The tumor microenvironment (TME) is composed of multiple infiltrating host cells (e.g., endothelial cells, fibroblasts, lymphocytes, and myeloid cells), extracellular matrix, and various secreted or cell membrane-presented molecules. Group 1 innate lymphoid cells (ILCs), which includes natural kille...

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Bibliographic Details
Main Authors: Gustavo Rodrigues Rossi, Edvaldo S. Trindade, Fernando Souza-Fonseca-Guimaraes
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Immunology
Subjects:
NK cells
tumor microenvironment
galectin
MMP
ADAM
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00073/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00073/full

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