Bile salts enhance the susceptibility of the peach allergenic lipid transfer protein, Pru p 3, to in vitro gastrointestinal proteolysis

Abstract Sensitisation to the lipid transfer protein Pru p 3 is associated with severe allergic reactions to peach, the proteins stability being thought to play a role in its allergenicity. Lipid binding increases susceptibility of Pru p 3 to digestion and so the impact of bile salts on the in vitro...

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Bibliographic Details
Main Authors: Kai Wang, Judit Gali-Moya, Maria Ruano-Zaragoza, Kathleen Cain, Giovanni D’Auria, Matthew Daly, Perdita Barran, René Crevel, E. N. Clare Mills
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-39599-0