Aggregation of alpha-synuclein in enteric neurons does not impact function in vitro
Abstract Recent evidence implicates a gut-first pathogenesis in the enteric nervous system (ENS) within a portion of PD patients, yet in vitro investigations have primarily focused on the central nervous system. Here, the preformed fibril (PFF) PD model is applied with co-administered groups of buty...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-12-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-26543-x |