Sex difference in pathology of the ageing gut mediates the greater response of female lifespan to dietary restriction

Women live on average longer than men but have greater levels of late-life morbidity. We have uncovered a substantial sex difference in the pathology of the aging gut in Drosophila. The intestinal epithelium of the aging female undergoes major deterioration, driven by intestinal stem cell (ISC) divi...

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Bibliographic Details
Main Authors: Jennifer C Regan, Mobina Khericha, Adam J Dobson, Ekin Bolukbasi, Nattaphong Rattanavirotkul, Linda Partridge
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-02-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/10956