Exploring the Effects of Cramped-Impact-Type Mechanical Action on Active Pharmaceutical Ingredient (Levofloxacin)—Prospects for Pharmaceutical Applications

Exploring the Effects of Cramped-Impact-Type Mechanical Action on Active Pharmaceutical Ingredient (Levofloxacin)—Prospects for Pharmaceutical Applications

Mechanochemistry is one of the ten great discoveries of green chemistry methods for synthesizing new substances. A drug substance from the fluoroquinolone group was exposed to high-intensity mechanical impacts using a laboratory knife mill for 21 min and constantly monitored by analyzing samples ext...

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Bibliographic Details
Main Authors: Elena Uspenskaya, Anastasia Simutina, Ekaterina Kuzmina, Vasilisa Sukhanova, Timur Garaev, Tatiana Pleteneva, Alena Koldina, Ekaterina Kolyabina, Gleb Petrov, Anton Syroeshkin
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Powders
Subjects:
mechanochemistry
tribochemichemistry
mechanical action
structural defects and impurities
dislocations
stress field
Online Access:https://www.mdpi.com/2674-0516/2/2/28

Internet

https://www.mdpi.com/2674-0516/2/2/28

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