Recombinant Antibody-Based and Computer-Aided Comprehensive Analysis of Antibody’s Equivalent Recognition Mechanism of Alternariol and Alternariol Monomethyl Ether

Recombinant Antibody-Based and Computer-Aided Comprehensive Analysis of Antibody’s Equivalent Recognition Mechanism of Alternariol and Alternariol Monomethyl Ether

Alternariol (AOH) and alternariol monomethyl ether (AME) are two main Alternaria mycotoxins that endanger human health. In this study, a single-chain antibody fragment (scFv) capable of equivalently and specifically recognizing AOH and AME was first expressed, and its equivalent recognition mechanis...

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Bibliographic Details
Main Authors: Zile Wang, Ling Chen, Pimiao Zheng, Jianyi Wang, Zhenhui Ren, Huixia Zhang, Liang Zhang, Haiyang Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Chemistry
Subjects:
molecular interaction
recognition mechanism
alternariol
alternariol monomethyl ether
single-chain antibody fragment
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2022.871659/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2022.871659/full

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