Tenuazonic acid: a promising antitubercular principle from Alternaria alternate

Tenuazonic acid: a promising antitubercular principle from Alternaria alternate

Bioactivity guided isolation of dichloromethane extract of <em>Alternaria alternata</em> identified tenuazonic acid (1) as potentially active against <em>Mycobacterium tuberculosis</em> H37Rv, MIC at 250 μg/mL concentration. This active metabolite 1, was also evaluated for os...

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Bibliographic Details
Main Authors: Visalakchi Sonaimuthu, Swati Parihar, Jay Prakash Thakur, Suaib Luqman, Dharmendra Saikia, Chandan S. Chinotiya, Muthumary Jhonpaul, Arvind Singh Negi
Format: Article
Language:English
Published: MDPI AG 2011-10-01
Series:Microbiology Research
Subjects:
Alternaria alternata, tenuazonic acid, Mycobacterium tuberculosis, antitubercular, toxicity, erythrocyte fragility
Online Access:http://www.pagepress.org/journals/index.php/mr/article/view/2886

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http://www.pagepress.org/journals/index.php/mr/article/view/2886

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