Excavatolide B Attenuates Rheumatoid Arthritis through the Inhibition of Osteoclastogenesis

Excavatolide B Attenuates Rheumatoid Arthritis through the Inhibition of Osteoclastogenesis

Osteoclasts are multinucleated giant cells of macrophage/monocyte lineage, and cell differentiation with the upregulation of osteoclast-related proteins is believed to play a major role in the destruction of the joints in the course of rheumatoid arthritis (RA). Pro-inflammatory cytokines, such as i...

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Bibliographic Details
Main Authors: Yen-You Lin, Yen-Hsuan Jean, Hsin-Pai Lee, Sung-Chun Lin, Chieh-Yu Pan, Wu-Fu Chen, Shu-Fen Wu, Jui-Hsin Su, Kuan-Hao Tsui, Jyh-Horng Sheu, Ping-Jyun Sung, Zhi-Hong Wen
Format: Article
Language:English
Published: MDPI AG 2017-01-01
Series:Marine Drugs
Subjects:
osteoclast
osteoclastogenesis
rheumatoid arthritis (RA)
excavatolide B
(Exc-B)
Online Access:http://www.mdpi.com/1660-3397/15/1/9

Internet

http://www.mdpi.com/1660-3397/15/1/9

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