Cas13d-mediated multiplex RNA targeting confers a broad-spectrum resistance against RNA viruses in potato

Abstract CRISPR-Cas systems endow the bacterial and archaeal species with adaptive immune mechanisms to fend off invading phages and foreign plasmids. The class 2 type VI CRISPR/Cas effector Cas13d has been harnessed to confer the protection against RNA viruses in diverse eukaryotic species. However...

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Bibliographic Details
Main Authors: Xiaohui Zhan, Wenting Liu, Bihua Nie, Fengjuan Zhang, Jiang Zhang
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05205-2