Genomic signature of MTOR could be an immunogenicity marker in human colorectal cancer

Genomic signature of MTOR could be an immunogenicity marker in human colorectal cancer

Abstract Background The mTOR signaling pathway plays an important role in cancer. As a master regulator, the status of MTOR affects pathway activity and the efficacy of mTOR inhibitor therapy. However, little research has been performed to explore MTOR in colorectal cancer (CRC). Methods In this stu...

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Bibliographic Details
Main Authors: Chenxing Wang, Batuer Aikemu, Yanfei Shao, Sen Zhang, Guang Yang, Hiju Hong, Ling Huang, Hongtao Jia, Xiao Yang, Minhua Zheng, Jing Sun, Jianwen Li
Format: Article
Language:English
Published: BMC 2022-07-01
Series:BMC Cancer
Subjects:
MTOR
Colorectal cancer
Immune infiltrates
Microsatellite instability
Whole-exome sequencing
Online Access:https://doi.org/10.1186/s12885-022-09901-w

Internet

https://doi.org/10.1186/s12885-022-09901-w

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