Fz2 and cdc42 mediate melanization and actin polymerization but are dispensable for Plasmodium killing in the mosquito midgut.

The midgut epithelium of the mosquito malaria vector Anopheles is a hostile environment for Plasmodium, with most parasites succumbing to host defenses. This study addresses morphological and ultrastructural features associated with Plasmodium berghei ookinete invasion in Anopheles gambiae midguts t...

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Autori principali: Shin-Hong Shiao, Miranda M A Whitten, Daniel Zachary, Jules A Hoffmann, Elena A Levashina
Natura: Articolo
Lingua:English
Pubblicazione: Public Library of Science (PLoS) 2006-12-01
Serie:PLoS Pathogens
Accesso online:http://europepmc.org/articles/PMC1757202?pdf=render