Characterization of novel stress degradation products of Bempedoic acid and Ezetimibe using UPLC–MS/MS: development and validation of stability-indicating UPLC method

Characterization of novel stress degradation products of Bempedoic acid and Ezetimibe using UPLC–MS/MS: development and validation of stability-indicating UPLC method

Abstract Background A receptive and easily comprehended technique was evolved for simultaneous assessment of Bempedoic acid and Ezetimibe and its impurities characterized by UPLC–MS/MS. Results This technique involves chromatographic separation with a C18 column of water symmetry (150 mm × 4.6 mm, 3...

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Bibliographic Details
Main Authors: Anuradha Vejendla, Subrahmanyam Talari, G. Ramu, Ch Rajani
Format: Article
Language:English
Published: SpringerOpen 2021-12-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
Bempedoic acid
Ezetimibe
Validation
Characterization
UPLC
UPLC–MS
Online Access:https://doi.org/10.1186/s43094-021-00381-6

Internet

https://doi.org/10.1186/s43094-021-00381-6

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