Analysis of serum proteomics data identifies a quantitative association between beta-defensin 2 at baseline and clinical response to IL-17 blockade in psoriatic arthritis

Analysis of serum proteomics data identifies a quantitative association between beta-defensin 2 at baseline and clinical response to IL-17 blockade in psoriatic arthritis

Objectives Despite several effective targeted therapies, biomarkers that predict whether a patient with psoriatic arthritis (PsA) will respond to a particular treatment are currently lacking.Methods We analysed proteomics data from serum samples of nearly 2000 patients with PsA in placebo-controlled...

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Bibliographic Details
Main Authors: Richard M Siegel, Marc Vandemeulebroecke, Mathias Cardner, Danny Tuckwell, Anna Kostikova, Pascal Forrer, Alain Marti, Enrico Ferrero
Format: Article
Language:English
Published: BMJ Publishing Group 2023-04-01
Series:RMD Open
Online Access:https://rmdopen.bmj.com/content/9/2/e003042.full

Internet

https://rmdopen.bmj.com/content/9/2/e003042.full

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