Transcription factor expression is the main determinant of variability in gene co‐activity

Abstract Many genes are co‐expressed and form genomic domains of coordinated gene activity. However, the regulatory determinants of domain co‐activity remain unclear. Here, we leverage human individual variation in gene expression to characterize the co‐regulatory processes underlying domain co‐acti...

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Bibliographic Details
Main Authors: Lucas vanDuin, Robert Krautz, Sarah Rennie, Robin Andersson
Format: Article
Language:English
Published: Springer Nature 2023-07-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.15252/msb.202211392