Association of the patterns of global DNA methylation and expression analysis of DNA methyltransferases in impaired spermatogenic patients

Objective: To analyze global DNA methylation along with DNA methyltransferases (DNMTs) expression at transcript level in patients with impaired spermatogenesis to dissect its role in pathophysiology of human male infertility. Method: The content of Global methylated cytosine (mC) was determined usin...

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Bibliographic Details
Main Authors: Deepika Jaiswal, Sameer Trivedi, Neeraj K. Agrawal, Kiran Singh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-12-01
Series:Asian Pacific Journal of Reproduction
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2305050015000214