Association of the patterns of global DNA methylation and expression analysis of DNA methyltransferases in impaired spermatogenic patients

Association of the patterns of global DNA methylation and expression analysis of DNA methyltransferases in impaired spermatogenic patients

Objective: To analyze global DNA methylation along with DNA methyltransferases (DNMTs) expression at transcript level in patients with impaired spermatogenesis to dissect its role in pathophysiology of human male infertility. Method: The content of Global methylated cytosine (mC) was determined usin...

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Bibliographic Details
Main Authors: Deepika Jaiswal, Sameer Trivedi, Neeraj K. Agrawal, Kiran Singh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-12-01
Series:Asian Pacific Journal of Reproduction
Subjects:
Methylation
Male infertility
Methyltransferases
Expression
Spermatogenesis
Testis
Online Access:http://www.sciencedirect.com/science/article/pii/S2305050015000214

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