S100A11 (calgizzarin) is released via NETosis in rheumatoid arthritis (RA) and stimulates IL-6 and TNF secretion by neutrophils

Abstract S100A11 (calgizzarin), a member of S100 family, is associated with several autoimmune diseases, including rheumatoid arthritis (RA). Neutrophil extracellular traps (NETs) are implicated in the pathogenesis of RA and in the externalization of some S100 family members. Therefore, we aimed to...

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Bibliographic Details
Main Authors: Adéla Navrátilová, Viktor Bečvář, Jiří Baloun, Dres Damgaard, Claus Henrik Nielsen, David Veigl, Karel Pavelka, Jiří Vencovský, Ladislav Šenolt, Lucie Andrés Cerezo
Format: Article
Language:English
Published: Nature Portfolio 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85561-3