Glial A30P alpha-synuclein pathology segregates neurogenesis from anxiety-related behavior in conditional transgenic mice

Glial A30P alpha-synuclein pathology segregates neurogenesis from anxiety-related behavior in conditional transgenic mice

In Parkinson's disease (PD) patients, alpha-synuclein (α-syn) pathology advances in form of Lewy bodies and Lewy neurites throughout the brain. Clinically, PD is defined by motor symptoms that are predominantly attributed to the dopaminergic cell loss in the substantia nigra. However, motor def...

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Bibliographic Details
Main Authors: Franz Marxreiter, Benjamin Ettle, Verena E.L. May, Hakan Esmer, Christina Patrick, Christine Lund Kragh, Jochen Klucken, Beate Winner, Olaf Riess, Jürgen Winkler, Eliezer Masliah, Silke Nuber
Format: Article
Language:English
Published: Elsevier 2013-11-01
Series:Neurobiology of Disease
Subjects:
Gliosis
Parkinson's disease
S100B
Transgenic
A30P alpha-synuclein
Conditional
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996113001988

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http://www.sciencedirect.com/science/article/pii/S0969996113001988

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