Integrated analyses of transcriptomics and network pharmacology reveal leukocyte characteristics and functional changes in subthreshold depression, elucidating the curative mechanism of Danzhi Xiaoyao powder

Integrated analyses of transcriptomics and network pharmacology reveal leukocyte characteristics and functional changes in subthreshold depression, elucidating the curative mechanism of Danzhi Xiaoyao powder

Objective: To investigate the molecular mechanism and identify potential drugs for subthreshold depression (SD), and elucidate the detalied mechanism of Danzhi Xiaoyao powder (DZXY) in SD. Methods: Using RNA-sequencing, we identified differentially expressed genes (DEGs) in leukocytes of SD compared...

Full description

Bibliographic Details
Main Authors: Kunyu Li, Leiming You, Jianhua Zhen, Guangrui Huang, Ting Wang, Yanan Cai, Yunan Zhang, Anlong Xu
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Journal of Traditional Chinese Medical Sciences
Subjects:
Subthreshold depression
Leukocyte
mRNA biomarker
CTRA
Transcription factor activity
CMap
Online Access:http://www.sciencedirect.com/science/article/pii/S2095754823000753

Internet

http://www.sciencedirect.com/science/article/pii/S2095754823000753

Similar Items