Vitronectin Destroyed Intestinal Epithelial Cell Differentiation through Activation of PDE4-Mediated Ferroptosis in Inflammatory Bowel Disease

Vitronectin Destroyed Intestinal Epithelial Cell Differentiation through Activation of PDE4-Mediated Ferroptosis in Inflammatory Bowel Disease

Objective. Vitronectin (VTN) has been reported to trigger cell pyroptosis to aggravate inflammation in our previous study. However, the function of VTN in inflammatory bowel disease (IBD) remains to be addressed. Methods. Real-time PCR and western blotting were performed to analyze VTN-regulated int...

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Bibliographic Details
Main Authors: Wenxu Pan, Li Xiang, Xinhua Liang, Wenjun Du, Junhong Zhao, Song Zhang, Xuan Zhou, Lanlan Geng, Sitang Gong, Wanfu Xu
Format: Article
Language:English
Published: Hindawi Limited 2023-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2023/6623329

Internet

http://dx.doi.org/10.1155/2023/6623329

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