Modulation of mitochondrial function by extracellular acidosis in tumor cells and normal fibroblasts: Role of signaling pathways

In many tumors pronounced extracellular acidosis resulting from glycolytic metabolism is found. Since several environmental stress factors affect the mitochondrial activity the aim of the study was to analyze the impact of acidosis on cellular oxygen consumption and which signaling pathways may be i...

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Bibliographic Details
Main Authors: Carmen Degitz, Sarah Reime, Christina-Marie Baumbach, Mandy Rauschner, Oliver Thews
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S147655862400040X