Deletion of Cardiomyocyte Glycogen Synthase Kinase-3 Beta (GSK-3β) Improves Systemic Glucose Tolerance with Maintained Heart Function in Established Obesity

Deletion of Cardiomyocyte Glycogen Synthase Kinase-3 Beta (GSK-3β) Improves Systemic Glucose Tolerance with Maintained Heart Function in Established Obesity

Obesity is an independent risk factor for cardiovascular diseases (CVD), including heart failure. Thus, there is an urgent need to understand the molecular mechanism of obesity-associated cardiac dysfunction. We recently reported the critical role of cardiomyocyte (CM) Glycogen Synthase Kinase-3 bet...

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Bibliographic Details
Main Authors: Manisha Gupte, Prachi Umbarkar, Anand Prakash Singh, Qinkun Zhang, Sultan Tousif, Hind Lal
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
GSK-3
high fat diet
obesity
cardiac function
Online Access:https://www.mdpi.com/2073-4409/9/5/1120

Internet

https://www.mdpi.com/2073-4409/9/5/1120

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