APRI and FIB-4 in the evaluation of liver fibrosis in chronic hepatitis C patients stratified by AST level.

BACKGROUND AND AIM:The aspartate aminotransferase (AST)-to-platelet ratio index (APRI) and fibrosis-4 index (FIB-4) are commonly used compound surrogates for advanced fibrosis in chronic hepatitis C (CHC) patients. However, the use of APRI and FIB-4 entails a risk of overestimating the fibrosis stag...

Full description

Bibliographic Details
Main Authors: Yi-Hao Yen, Fang-Ying Kuo, Kwong-Ming Kee, Kuo-Chin Chang, Ming-Chao Tsai, Tsung-Hui Hu, Sheng-Nan Lu, Jing-Houng Wang, Chao-Hung Hung, Chien-Hung Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6023204?pdf=render