Polyoxometalate-Decorated Gold Nanoparticles Inhibit β-Amyloid Aggregation and Cross the Blood–Brain Barrier in a µphysiological Model

Polyoxometalate-Decorated Gold Nanoparticles Inhibit β-Amyloid Aggregation and Cross the Blood–Brain Barrier in a µphysiological Model

Alzheimer’s disease is characterized by a combination of several neuropathological hallmarks, such as extracellular aggregates of beta amyloid (Aβ). Numerous alternatives have been studied for inhibiting Aβ aggregation but, at this time, there are no effective treatments available. Here, we develope...

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Bibliographic Details
Main Authors: Marta Perxés Perich, Sujey Palma-Florez, Clara Solé, Sara Goberna-Ferrón, Josep Samitier, Pedro Gómez-Romero, Mònica Mir, Anna Lagunas
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Nanomaterials
Subjects:
nanovehicle
gold nanoparticles
polyoxometalates
β-amyloid
blood–brain barrier organ-on-a-chip
Online Access:https://www.mdpi.com/2079-4991/13/19/2697

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https://www.mdpi.com/2079-4991/13/19/2697

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