Effect of parental adverse childhood experiences on intergenerational DNA methylation signatures from peripheral blood mononuclear cells and buccal mucosa

Abstract In this study, the effect of cumulative ACEs experienced on human maternal DNA methylation (DNAm) was estimated while accounting for interaction with domains of ACEs in prenatal peripheral blood mononuclear cell samples from the Maternal and Developmental Risks from Environmental Stressors...

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Bibliographic Details
Main Authors: Sahra Mohazzab-Hosseinian, Erika Garcia, Joseph Wiemels, Crystal Marconett, Karina Corona, Caitlin G. Howe, Helen Foley, Shohreh F. Farzan, Theresa M. Bastain, Carrie V. Breton
Format: Article
Language:English
Published: Nature Publishing Group 2024-02-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-024-02747-9