Sustained delivery of recombinant human bone morphogenetic protein‐2 from perlecan domain I ‐ functionalized electrospun poly (ε‐caprolactone) scaffolds for bone regeneration

Abstract Background Biomaterial scaffolds that deliver growth factors such as recombinant human bone morphogenetic proteins‐2 (rhBMP‐2) have improved clinical bone tissue engineering by enhancing bone tissue regeneration. This approach could be further improved if the controlled delivery of bioactiv...

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Bibliographic Details
Main Authors: Yu‐Chieh Chiu, Eliza L. Fong, Brian J. Grindel, Fred K. Kasper, Daniel A. Harrington, Mary C. Farach‐Carson
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Journal of Experimental Orthopaedics
Subjects:
Online Access:https://doi.org/10.1186/s40634-016-0057-1