Successfully treated with siltuximab and prednisone in a 7-year-old girl with DOCK8-deficiency presenting as recurrent wart-like lesions: a case report

Successfully treated with siltuximab and prednisone in a 7-year-old girl with DOCK8-deficiency presenting as recurrent wart-like lesions: a case report

Dedicator of cytokinesis 8 (DOCK8) deficiency represents a primary immunodeficiency with a wide range of clinical symptoms, including recurrent infections, atopy, and increased malignancy risk. This study presents a case of a 6-year-old girl with DOCK8 deficiency, characterized by severe, treatment-...

Full description

Bibliographic Details
Main Authors: Zhe Sun, Ruoqu Wei, Chaolan Pan, Cheng Ni, Xue Zhang, Wenbin Guan, Ruhong Cheng, Yan Gu, Hong Yu, Kejun He, Zhen Zhang, Xia Yu, Zhirong Yao
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-07-01
Series:Frontiers in Immunology
Subjects:
DOCK8 deficiency
herpetic infections
IL-6
siltuximab
primary immunodeficiency
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1414573/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1414573/full

Similar Items