Single-Stranded DNA-Binding Transcriptional Regulator FUBP1 Is Essential for Fetal and Adult Hematopoietic Stem Cell Self-Renewal

The ability of hematopoietic stem cells (HSCs) to self-renew is a prerequisite for the establishment of definitive hematopoiesis and life-long blood regeneration. Here, we report the single-stranded DNA-binding transcriptional regulator far upstream element (FUSE)-binding protein 1 (FUBP1) as an ess...

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Bibliographic Details
Main Authors: Uta Rabenhorst, Frederic B. Thalheimer, Katharina Gerlach, Marek Kijonka, Stefanie Böhm, Daniela S. Krause, Franz Vauti, Hans-Henning Arnold, Timm Schroeder, Frank Schnütgen, Harald von Melchner, Michael A. Rieger, Martin Zörnig
Format: Article
Language:English
Published: Elsevier 2015-06-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715005744